什么是DEHP？
DEHP是家用化学物质的一部分，叫做邻苯二甲酸盐。这些化学物质用来使PVC塑料变得柔软且富有弹性。由于这中化学物质不与塑料融合在一起，所以DEHP可以从产品中脱离，进入患者体内。.
暴露在DEHP之中会有哪些危害？
根据动物研究，暴露在DEHP之中的副作用包括性器官的变化而导致生育能力下降、呼吸窘迫、肾和肝脏功能的退化。但由于DEHP可能会影响到新生儿发育不全的器官，因此人们对新生儿的关注度最高。
如何减少接触？
其目标在于消除在新生儿重症监护室中含有DEHP的所有产品。为了达到该目标，英特赛克已经为新生儿研发出一种不含邻苯二甲酸盐（DEHP）系列的鼻氧管。
消除在新生儿重症监护室中的DEHP，该做些什么？
更安全的PVC产品的替代品存在，意味着针对新生儿重症监护室严谨的做法，是引进不含邻苯二甲酸盐/PVC的产品。
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Durmaz E, Ozmert EN, Erkekoglu P, Giray B, Derman O, Hincal F, Yurdakok K.
Plasma phthalate levels in pubertal gynecomastia.
Pediatrics 2010; 125(1): e122-e129
Green R, Hauser R, Calafat AM, Weuve J, Schettler T, Ringer S, Huttner K, Hu H.
Use of di(2-ethylhexyl)phthalate-containing medical products and urinary levels of mono(2-ethylhexyl)phthalate in neonatal intensive care unit infants.
Environmental Health Perspectives 2005: 113(9): 1222-1225
Hill SS, Shaw BR, Wu AHB.
The clinical effects of plasticizers, antioxidants, and other contaminants in medical polyvinyl chloride tubing during respiratory and non-respiratory exposure.
Clinica Chimica Acta 2001; 304: 1-8
Hill SS, Shaw BR, Wu AHB.
Plasticizers, antioxidants, and other contaminants found in air delivered by PVC tubing used in respiratory therapy.
Biomedical Chromatography 2003; 17: 250-262
Hu GX, Lian QQ, Ge RS, Hardy DO, Li XK.
Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence.
Trends in Endocrinology and Metabolism 2009; 20(3): 139-145
Swan SH, Liu F, Hines M, Kruse RL, Wang C, Redmon JB, Sparks A, Weiss B.
Prenatal phthalate exposure and reduced masculine play in boys.
International Journal of Andrology 2009; 32: 1-9
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